Last Updated on December 27, 2017 by Joseph Gut – thasso December 25, 2017 – The American Food & Drug Administration (FDA) has approved two genetic tests to identify genetic alterations in tumors.  The FoundationOne CDx (F1CDx) genomic test and the …

FDA-cleared genomic profiling tests to guide cancer treatment Read more »

Last Updated on December 21, 2017 by Joseph Gut – thasso Dezember 21, 2017 – Erdheim–Chester disease ((ECD), also known as Erdheim–Chester syndrome or polyostotic sclerosing histiocytosis) is a form of a bone marrow borne blood cancer. It is a …

Vemurafenib (Zelboraf) for BRAF V600E positive Erdheim-Chester Disease (ECD) Read more »

Last Updated on December 23, 2017 by Joseph Gut – thasso December 21, 2017 – No pain on gain. This headline might not at all apply for this Italian family. In a paper just published in the Journal Brain, researchers …

Marsili Syndrome: A mutation in the ZFHX2 gene leaves Italian family painless Read more »

Last Updated on December 23, 2017 by Joseph Gut – thasso December 20, 2017 –  The American Food & Drug Administration (FDA) has just approved  a novel gene therapy to treat patients with a rare form of inherited vision loss. …

Voretigene Neparvovec-Rzyl (Luxturna): Gene therapy to treat inherited vision loss Read more »

Last Updated on December 23, 2017 by Joseph Gut – thasso  December 16, 2017 – As recent as of December 14, 2017, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a …

X-linked Hypophosphatemia: Burosumab (Crysvita) to the rescue Read more »

Last Updated on December 23, 2017 by Joseph Gut – thasso December 09, 2017 – Newest research has revealed that a DNMT3B gene variant influences nicotine dependence identified in people of European (Caucasian) descent and African-American decent as well. Thus, …

DNMT3B gene variant influences nicotine dependence Read more »

Last Updated on December 23, 2017 by Joseph Gut – thasso December 05, 2017 – We are entering the age of precision medicine, in which diagnosis and therapy decisions for each patient will be based on detailed genetic and molecular fingerprints. …

Gene expression and ethnicity: Does it matter? Read more »

Last Updated on February 13, 2018 by Joseph Gut – thasso December 01, 2017 – The placebome is a new game in town. That is where genetics and the placebo effect meet. The underlying discipline of study may well be …

Placebomics: Where placebo and genetics meet Read more »

Last Updated on April 10, 2018 by Joseph Gut – thasso November 23, 2017 – We all have heard of it: While in full action of the game, a young soccer player collapsed on the field and died. Same for …

The nightmare: Sudden cardiac arrest in competitive sports Read more »

Last Updated on November 24, 2017 by Joseph Gut – thasso November 24, 2017 – New research indicates that one-size treatment for one form of blood cancer likely does not fit all, particularly when it comes to ethnic differences of …

Cancer is not like cancer: Ethnic background matters Read more »