October 28, 2017 – How Precise is Precision Medicine When Applied to Diverse Populations? This was the question raised in a very recent article published in Front Line Genomics that is based an an according study published online October 19, 2017, …

Is precision medicine un-precise when applied to diverse world populations? Read more »

 July 18, 2017 – According to a new study just published in the Journal of  Psychiatric Research, a single-nucleotide polymorphism (SNP), rs300774, which previously had been identified as a marker for suicide in people with bipolar disorder (BD), also predicts suicide …

Genetic Biomarker Tied to Suicide Risk in Schizophrenia Read more »

June 09, 2017 –  It’s only a couple of days that the American Food & Drug Administration (FDA) approved for the first time a cancer treatment for any solid tumor, irrespective of the tumor’s original location, as long as the targeted tumor is …

Biomarker-guided Larotrectinib for all cancer types? Read more »

Mai 07, 2017 – Genetics- and/or genomics-based approaches are penetrating every single aspect of human life. In contrast to the term theragenomics (therapy decisions with the help of  genetic/genomic information obtaineble from the patient concerned), we may coin the term …

Lifeomics: Epigenetic DNA methylation-based life insurance? Read more »

May 03, 2017 – Is there a genetic predisposition for usage of social media? The answer may be a qualified YES. It’s easy to think in terms of linking genetics to behavior in simple ways. Are you calm or do …

Is there a genetic predisposition for usage of social media? Read more »

April 22, 2017 – An open source pharma roadmap: This is the title of a conceptual paper just published by Balasegaram M, et. al., in the open access journal PLoS Medicine (2017) 14(4), freely accessible to everybody here. The essay …

Open source pharma: A gem for patients? Read more »

April 04, 2017 – Personalized medicine, also referred to as precision medicine, incorporates the individual patient’s characteristics into treatment, rather than relying on population means. Over the past several years, it has become a significant focus for research. Developments in pharmacogenomics, …

Children: Is there personalized medicine for children too? Read more »

March 25, 2017 – The Boston-based start up company FDNA has launched an app-based tool for clinicians using facial recognition, artificial intelligence (AI) and genetic big data to improve rare disease diagnosis and treatment. If it were not for an incredible …

Face2Gene: tool using facial recognition, AI and genetic big data to improve rare disease diagnosis and treatment Read more »

March 23, 2017 – For sure across the United States, but by a fair assumption worldwide also, late-onset Alzheimer’s disease (AD) is the most common form of dementia. There is a strong need for in vivo markers for AD risk stratification …

Polygenic hazard scores in age-associated Alzheimer’s disease Read more »

March 11, 2017 – This is very good news for a heavy coffee drinker like myself: scientists have identified 24 compounds that increase the brain’s production of the enzyme NMNAT2, which helps prevent the formation of these tangles associated with …

Caffeine could help to protect against dementia Read more »