Blog Archives

Black Gorilla, Big N Hard, Rize N Shine, and the likes: Fraudulent health business

November 05, 2017 – The commercial names are creative, no doubt, and we like particularly “Black Gorilla”. However, time and time again, health authorities all over have to issue foreign product alerts, warning consumers, patients, and the public at large about products that claim to be “all natural”

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Is there a risk of melanoma with erectile dysfunction drugs?

November 01, 2017 – According to the watch list of the American Food & Drug Administration (FDA) for drugs with possible safety issues from January to March 2016,

the FDA was looking at the possible link between various drugs in the phosphodiesterase-5 (PDE-5) inhibitors class and melanoma as a serious adverse effect.

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Obeticholic Acid (Ocaliva): Is there a serious drug safety problem?

September 30, 2017 – Obeticholic acid (Ocaliva) was approved by the American Food & Drug Administration (FDA) in May 2016 for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adult  patients with an inadequate response to UDCA,

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Risk of leg and foot amputations under Canagliflozin (Invokana, Invokamet)

May 17, 2017 – Following up on an earlier Drug Safety Communication from May 2016 and based on new data from two large clinical trials, the American Food & Drug Administration (FDA) has concluded that the type 2 diabetes medicines Canagliflozin (Invokana), Canagliflozin/Metformin (Invokamet),  and Canagliflozin/Metformin (Invokamet XR) cause an increased risk of leg and foot amputations.

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Living theragenomics: Dangers of codeine and tramadol medicines in children

April 23, 2017 – This is a Safety Announcement from April 20, 2017, by the American Food & Drug Administration (FDA) to the fact that FDA further restricts use of prescription codeine pain and cough medicines and tramadol pain medicines in children and recommends against their use in breastfeeding women.

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A price for women’s beauty: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)

March 27, 2017 – We all adore the beauty of women. Some women may feel that they need some help from medical practice to become the most  beautiful. When it comes to corrective breast implants, the price may be very high in some rare cases, where women develop breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) as a very serious,

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Risk of severe if not fatal skin reactions with Pembrolizumab (Keytruda)

March 21, 2017 – Health Canada just communicated this important safety information: Cases of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) under treatment of patients with Pembrolizumab (Keytruda) have been reported internationally in the clinical trials and post-marketing setting.

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BCR-ABL Tyrosine Kinase Inhibitors: Danger of HBV-Reactivation

October 12, 2016 – This is a communication from Health Canada, issued in May 2016, concerning the danger of reactivation of hepatitis B virus hep-i(HBV) infection in patients treated with BCR-ABL tyrosine kinase inhibitors (TKIs) and geared towards healthcare professionals (medical oncologists,

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FDA warns about the risk of HBV reactivation in patients treated with DAA for HCV-infection

October 05, 2016 – Here, we make available to our readers a Drug Safety Communication by the American Food & Drug Administration (FDA), where FDA warns about the risk of hepatitis B virus (HBV) reactivation in some patients treated with direct-acting antivirals (DAA) for hepatitis hepatitis-c-iC virus (HCV)-infection.

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The opioid epidemic: Is there a never ending sad story?

September 01, 2016 – This is what we learned this morning and sadly, the issue of opioids use in the population along with its fatal outcomes seems never to stop.  The American Food & Drug Asministation (FDA) requires, according to a press release this morning,

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  • Study explores cognitive function in people with mental illness January 22, 2020
    A study funded by the Veterans Administration and directed by researchers at the University of Miami Miller School of Medicine has shown few differences in the profiles of genes that influence cognition between people with schizophrenia, bipolar disorder and the general population. This surprising finding could provide new insights into therapies designed to improve cognition. […]
  • Hope for patients with a rare genetic condition linked to severe infections January 22, 2020
    A team of researchers at CHU Sainte-Justine and Université de Montréal has shed light on the mechanisms that underlie a rare genetic condition by creating the first cellular model of the disease. The study's findings were published today in the Journal of Allergy and Clinical Immunology.
  • Avatar worms help to identify factors that modify genetic diseases January 21, 2020
    Often, patients from the same family and carriers of the same genetic mutation, develop a disease differently. This disparity may be due to the existence of mutations in other secondary genes, which influence the onset and progression of the disease caused by the main mutation. As an example, members of a family who are carriers […]
  • Algorithm turns cancer gene discovery on its head January 21, 2020
    A method for finding genes that spur tumor growth takes advantage of machine learning algorithms to sift through reams of molecular data collected from studies of cancer cell lines, mouse models and human patients.
  • Blood test for eight gene signatures could predict onset of tuberculosis January 21, 2020
    Scientists at UCL have shown a blood test could predict the onset of tuberculosis three to six months before people become unwell, a finding which could help better target antibiotics and save countless lives.
  • Sea level rise could reshape the United States, trigger migration inland January 22, 2020
    New study is the first to use machine learning to project migration patterns resulting from sea-level rise. Researchers found the impact of rising oceans will ripple across the country, beyond coastal areas at risk of flooding, as affected people move inland. Popular relocation choices will include land-locked cities such as Atlanta, Houston, Dallas, Denver and […]
  • Acousto-optic modulation of photonic bound state in the continuum January 22, 2020
    Applying bound states in the continuum (BICs) in photonic integrated circuits enables low-loss light guidance and routing in low-refractive-index waveguides on high-refractive-index substrates. Here, we demonstrate high-quality integrated lithium niobate microcavities with circulating BICs and further acousto-optically modulate these BICs by surface acoustic waves. The acousto-optic coupling is well situated in the resolved-sideband regime, which […]
  • Ben-Gurion University researchers slash pre-drug screening time from years to days January 22, 2020
    'Our new approach will increase the understanding of the mechanisms and evolutionary origins of specific PPIs, and facilitate the rational design of specific inhibitors that can discriminate between structurally similar protein targets,' says Professor Niv Papo of BGU's Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute for Biotechnology in the Negev […]
  • Even after death, animals are important in ecosystems January 22, 2020
    Animal carcasses play an important role in biodiversity and ecosystem functioning. Scientists from the German Centre for Integrative Biodiversity Research (iDiv) and the University of Groningen have published these findings in PLOS ONE. Carcasses not only provide food for carrion-eating animals. Their nutrients also increase the growth of surrounding plants, which attracts many herbivorous insects […]
  • Study shines light on spread of Candida auris January 22, 2020
    Candida auris is capable of forming high burden biofilms, which may help explain why this fungal pathogen is spreading in hospitals worldwide, according to a study published this week in mSphere, an open-access journal of the American Society for Microbiology. The research also establishes a new model to investigate the spread of this emerging fungal […]
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