Blog Archives

Wo sich Porträtfotos mit Genetik und KI treffen

13. Juni 2019 – Das ist einfach faszinierende Wissenschaft und Medizin. Die Forscher testen neuronale Netzewerke, die automatisch Porträtfotos mit genetischen und phänotypischen Patientendaten kombinieren, um mit Hilfe der künstlichen Intelligenz (KI) eine endgültige Diagnose erblich bedingter seltener Krankheiten zu erhalten. In einer im Journal of Genetics in Medicine veröffentlichten Studie mit 679 Patienten mit 105 seltenen Krankheiten hat ein interdisziplinäres Wissenschaftlerteam gezeigt,

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Iberogast: Pharmafirmen wie Autobauer. Täuschung der Kunden und Patienten für Profit

20. Oktober 2018 – Das in der traditionellen chinesischen Medizin und in der Naturheilkunde mit verschiedenen therapeutischen Wirkungen assoziierte Schöllkraut hat eine potenziell lebertoxische Wirkung. Aufgrund dieser Lebertoxizität von Schöllkraut wurde bereits 2008 allen Phytopharmaka mit einer Tagesdosis von mehr als 2,5 mg Chelidonium-Gesamtalkaloiden die Zulassung entzogen.

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Immunvermittelte nekrostisierende Myopathie: Eine seltene, jedoch bedrohliche Nebenwirkung unter Statin-Therapie

13. November 2015 – In den letzten Jahren wurden Statine (HMG-CoA-Reduktasehemmer) als ein möglicher Auslöser der seltenen immunvermittelten nekrotisierenden Myopathie (englisch als immune-mediated necrotising myopathy (IMNM) bezeichnet) identifiziert.

Swissmedic (Das Schweizerische Heilmittelinstitut) hat dazu am 21. Oktober 2015 eine sogenannte HPC (Health Profesional Communication) veröffentlicht.

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Rodapitant (Varubi) als eine neue Behandlung für Übelkeit und Erbrechen nach Chemotherapie zugelassen

2. September 2015 – phase die US Food and Drug Administration zugelassenen Rodapitant (Varubi) um zu vermeiden verzögert, Chemotherapie-induzierter Übelkeit und Erbrechen (Erbrechen). Rodapitant (Varubi) wird bei Erwachsenen in Kombination mit anderen Drogen (brechreizhemmende Agenten), die Übelkeit zu verhindern genehmigt und Erbrechen im Zusammenhang mit aus- und wiederholen-Kurse von Erbrochenem-induzierende (emetogenen und hoch emetogenen) Krebs-Chemotherapie.

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Droge-Sicherheit-Kommunikation: DPP-4-Inhibitoren für Typ 2-Diabetes können schwere Gelenkschmerzen verursachen.

29. August 2015 – dies immerhin also gute Nachrichten für Typ-2-Diabetikern über DPP-4-Hemmer Medikamente möglicherweise nicht. Der amerikanischen Food and Drug Administration (FDA) warnt, dass die pharmakologisch wirksamen Bestandteile (PAI) Sitagliptin, Saxagliptin Linagliptin und Alogliptin mit Typ 2 Diabetes Medikamente Gelenkschmerzen verursachen können, die schwere und behindernden sein können.  

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A potentially life-saving drug safety communication: FDA strengthens warning of increased chance of heart attack or stroke on non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs)

July 15, 2015 – This post comes directly from FDA, and it may not only be live-saving information for patients in the US, but all over the world, including the Africa’s, Europe, and Asia. 

The ISSUE: FDA is strengthening an existing drug label warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke.

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Cangrelor (Kengreal) a newly approved antiplatelet drug used during PCI heart procedure

June 26, 2015 –  The following is good news for patients who will need percutaneous coronary intervention (PCI), however, bleeding problems are not completely resolved. But see for yourself.

The U.S. Food and Drug Administration just approved Cangrelor (Kengreal), an intravenous antiplatelet drug that prevents formation of harmful blood clots in the coronary arteries,

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Eliglustat [Cerdelga] approved for the treatment of a form of Gaucher Disease

August 22. 2014 – On August 19, 2014, the U.S. Food and Drug Administration approved Cerdelga (eliglustat) for the long-term treatment of adult patients with the Type 1 form of Gaucher disease, a rare genetic disorder.

Gaucher disease occurs in people who do not produce enough of an enzyme called glucocerebrosidase.

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FDA approves first non-invasive DNA screening test for colorectal cancer

August 11. 2014 – The U.S. Food and Drug Administration today approved Cologuard, the first stool-based colorectal screening test that detects the presence of red blood cells and DNA mutations that may indicate the presence of certain kinds of abnormal growths that may be cancers such as colon cancer or precursors to cancer.

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Genetic Trigger Discovered For Most Common Form of Mental Disability and Autism

March 08, 1014 – The following article just appeared in PsyBlog and provides highly interesting reading in relation to newly discovered molecular mechanisms in the etiology of (possibly individualized) disease predispositions. Very exciting.

The most common form of intellectual disability is caused by a mechanism which shuts of an associated gene,

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  • Researchers find genetic links to child obesity across diverse ethnic groups August 22, 2019
    An international team of researchers who analyzed data across multiple ethnicities has produced the largest genetic study to date associated with common childhood obesity. The Early Growth Genetics (EGG) Consortium discovered a robust new signal, fine-mapped previously reported genetic variants, and added to evidence that genetic influences on obesity operate across the lifespan.
  • Researchers develop model to personalize radiation treatment August 22, 2019
    A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with specific mutations or patterns. However, this same personalized strategy has not translated to radiation therapy, and a one-size-fits-all approach for most patients is still common practice. Moffitt Cancer Center […]
  • How our genes and environment influence BMI and height August 22, 2019
    Environmental conditions influence our body mass index (BMI) by increasing or decreasing the effect of inherited genetic variations, University of Queensland researchers have discovered.
  • Genetic testing and family tree research are revealing painful family secrets, research says August 22, 2019
    Genealogical research and genetic testing are revealing skeletons in family closets and causing rifts among members, a new study shows.
  • Researchers use single-cell sequencing to get a better look at human embryo implantation August 22, 2019
    A team of researchers affiliated with multiple institutions in China has used single-cell sequencing to learn more about the human embryo during implantation in the uterus. In their paper published in the journal Nature, the group describes sequencing thousands of human embryo cells from before, during and after implantation, and what they learned from it.
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