January 21, 2017 –There are roughly one million suicides worldwide annually, corresponding to an estimated yearly mortality rate of 14.5 deaths per 100,000 people in the general population. In Europe, suicide represents the second leading cause of mortality in the 14–24 …

Some practical thoughts about suicide: Before jumping, you should consult your genes Read more »

September 19, 2016 – This post presents below a virtually unedited announcement by the American Food & Drug Administration (FDA) concerning Duchenne Muscular Dystrophy (DMD) therapy  option which gives much hope for at least some of the affected patients. However, be …

Eteplirsen (Exondys 51) for Duchenne Muscular Dystrophy (DMD) approved Read more »

September 06, 2016 – Genetic mutations associated with acquired resistance to PD-1 blockade in melanoma have been suspected to be involved in the clinical observation that while approximately 75% of objective responses to anti–programmed death 1 (PD-1) therapy in patients with …

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma Read more »

September 04, 2016 – Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University, who last year identified new gene mutations unique to colon cancers in African Americans, have found that …

Adverse clinical outcome associated with mutations in colorectal cancers of African Americans Read more »

July 9, 2016 – This is a huge step into the future of theragenomic and personalized medicine and individualized drug safety. In support of the President’s Precision Medicine Initiative (PMI), the American Food & Drug Administration (FDA) just issued two …

Precision Medicine Initiative: draft guidances issued Read more »

May 20, 2016 – Your gender-stereotypic genes may be giving you a leg up in dating. Researchers have used a real-life speed-dating scenario to test how genetics influence mate selection. According to their findings, just published in the Journal “Human …

We knew it all along: It’s all in the genes, and success in dating is no exception Read more »

April 02, 2016 – The European Medicines Agency (EMA) has recommended granting a marketing authorisation in the European Union (EU) for a new gene therapy for the treatment of patients with adenosine-deaminase-deficient severe combined immunodeficiency (ADA-SCID), who have no matching donor for a stem cell …

New hope for children with the ultra-rare immune disorder ADA-SCID: Gene therapy Strimvelis recommended for approval by EMA’s CHMP Read more »

August 15, 2015 – Please find here the abstract of an recent article which is concerned with the genetic basis of smoking and the prospects of smoking cessation therapies in individual smokers.  The author of this blog thought it worthwhile …

Theragenomic Medicine: Where there is a cigarette, there is smoke. How much, that may be in your genes. Read more »

September 27, 2014 – A while ago (August 2012),  the American Food and Drug Administration (FDA) was assessing and reporting on the (possibly fatal) risks associated with the use of codeine containing medicines in children who are phenotypically members of the …

FDA Drug Safety Communication: Codeine use in certain children after tonsillectomy and/or adenoidectomy may lead to rare, but life-threatening adverse events or death Read more »

May 01, 2014 – This is a fantastic article on a very difficult to understand topic, with often very sad outcomes.  The source of the article is Medscape and it reveals how combined efforts from different scientific appoaches may lead …

Just Wait A Little Longer: Suicide Biomarkers Getting Closer to the Clinic Read more »