July 02, 2017 – The APP A673T allelic variant of the amyloid precursor protein (APP) gene which in earlier research has been shown to protect against Alzheimer’s Disease (AD) is associated with decreased levels of plasma amyloid β (Aβ), according …

APP A673T carriers: Lower Aβ levels protective against Alzheimer’s Disease? Read more »

June 23, 2017 – According to a new study involving 73 people between 50 and 83 years of age, just published in The Journals of Gerontology, Series B: Psychological and Social Sciences, more frequent sexual activity can boost brain power (i.e., …

Sexual activity to boost brain power of the elderly Read more »

June 20, 2017 – Insomnia is one of the most common complaint people have about their health. In contrast to common belief and often assumed by the affected sufferers, however, insomnia seems not to be just all in the patients …

Genetic background of insomnia: At least partially Read more »

June 16, 2017 – Patient education in pharmacogenetics, the central component of theragenomic and personalized medicine and individualized drug safety is an important issue. Not only needs the individual patient to understand what pharmacogenetics, or more precisely, pharmacogenetic testing can …

Development of a patient education video about pharmacogenetics Read more »

June 09, 2017 –  It’s only a couple of days that the American Food & Drug Administration (FDA) approved for the first time a cancer treatment for any solid tumor, irrespective of the tumor’s original location, as long as the targeted tumor is …

Biomarker-guided Larotrectinib for all cancer types? Read more »

May 24, 2917 – The American Food & Drug Administration (FDA) just approved a major extension of the clinical indications for Pembrolizumab (Keytruda). For the first time,  a cancer treatment has been approved for any solid tumor, irrespective of the tumor’s …

First cancer treatment for any solid tumor with MSI-H or dMMR approved Read more »

May 18, 2017 – Ivacaftor (Kalydeco) is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator indicated for the treatment of cystic fibrosis (CF) in patients age 2 years and older who are carriers one of the following mutations in the CFTR gene: …

Theragenomics: Ivacaftor (Kalydeco) in the CFTR mutation-based treatment of cystic fibrosis (CF) Read more »

18 May 2017 – According to a paper just published in PLOS One, research team from the University of Zurich found that individuals who agree to openly share their direct-to-consumer (DTC) genetic testing data are apparently most interested in learning more …

Motivation and dangers of sharing personal genetic data in the open space Read more »

May 14, 2017 – Hypertension is a leading cause of global disease, mortality, and disability. Individuals of African descent suffer a disproportionate burden of hypertension and its complications. To date, there has been little information on the possible genetic background (i.e., …

Populations of African descent: New trait loci for hypertension Read more »

Mai 07, 2017 – Genetics- and/or genomics-based approaches are penetrating every single aspect of human life. In contrast to the term theragenomics (therapy decisions with the help of  genetic/genomic information obtaineble from the patient concerned), we may coin the term …

Lifeomics: Epigenetic DNA methylation-based life insurance? Read more »