November 03, 2019 – Cystic fibrosis (CF) is a lethal, inherited genetic disease affecting more than 70,000 people worldwide. It is usually diagnosed in childhood and causes abnormal buildup of thick mucus in the lungs and digestive tract that leads …

In Caribbeans cystic fibrosis (CF) is driven by very rare CFTR mutations Read more »

October 20, 2019 – Sequencing African genomes yields new data resource with broad applicability. By collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing genomes from regions and countries across Africa. These findings will enable …

Hidden secrets in African genomes revealed by large scale sequencing Read more »

August 07, 2019 – Blonde hair is a rare human phenotype found almost exclusively in Europe and Oceania. Human pigmentation varies considerably within and among populations and is a function of both variation in exposure to ultraviolet radiation (UVR) and …

Black people with natural blonde hair – Everything is possible in genetics Read more »

August 03, 2019 – Africa is considered the original cradle of all humanity, to which all humans can trace their genetic origin. This may be very interesting in the context of diseases that are due to genetic predispositions both in …

ZRANB3 in African Populations: New Type 2 Diabetes risk locus identified Read more »

August 01, 2019 – Post-Traumatic Stress Disorder (PTSD) is a mental disorder that can develop after a person is exposed to a traumatic event, such as sexual assault, warfare, traffic collisions, or other threats on a person’s life. Symptoms may include disturbing …

Risk loci for post-traumatic stress disorder (PTSD) Read more »

May 10, 2018 – A seemingly higher incidence of prostate cancer and resulting fatalities in African-American men than in European-Amcerican men has been noted for quite some time. New research published in Molecular Oncology may help explain why African American …

Ethnic disparities in the occurrence of prostate cancer Read more »

February 04 –Malaria, caused by Plasmodium falciparum parasites, is a major cause of mortality and morbidity in endemic countries of Sub-Saharan Africa with a disproportional burden of 90% of the estimated 212 million annual cases and 92% of 429,000 annual …

Protection from severe malaria associated with novel genetic polymorphisms Read more »

December 09, 2017 – Newest research has revealed that a DNMT3B gene variant influences nicotine dependence identified in people of European (Caucasian) descent and African-American decent as well. Thus, a DNA variant, located in the DNMT3B gene and commonly found …

DNMT3B gene variant influences nicotine dependence Read more »

December 05, 2017 – We are entering the age of precision medicine, in which diagnosis and therapy decisions for each patient will be based on detailed genetic and molecular fingerprints. Unfortunately, much of the revolutionary work that underpins precision medicine has …

Gene expression and ethnicity: Does it matter? Read more »

November 24, 2017 – New research indicates that one-size treatment for one form of blood cancer likely does not fit all, particularly when it comes to ethnic differences of patients.  Thus, African-American men are three times more likely to be …

Cancer is not like cancer: Ethnic background matters Read more »