the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
January 08, 2023 – In precision and/or targeted medicine of today, physicians typically start out with the determination of the patients phenotypic expression of a disease (i.e., establish a clinical finding) and then go on into finding out the patients genetic …
Genomic variants traced forward to genetic disorders: A new approach? Read more »
September 25, 2022 – Nearly 2000 years ago the Roman scholar and natural philosopher Pliny the Elder wrote in his Natural History: “Ex Africa surgit semper aliquid novi” (from Africa there is always something new). This quote beautifully applies to …
December 28, 2020 – Some 95% of people have gene variants that may negatively affect their response to at least one drug, leading to unexpected or adverse drug reactions (ADRs) or, if unlucky, to a serious, if not fatal, adverse …
Genetics behind some serious adverse drug reactions (SADRs) Read more »
August 01, 2019 – Post-Traumatic Stress Disorder (PTSD) is a mental disorder that can develop after a person is exposed to a traumatic event, such as sexual assault, warfare, traffic collisions, or other threats on a person’s life. Symptoms may include disturbing …
Risk loci for post-traumatic stress disorder (PTSD) Read more »
July 26, 2019 – “Blockchains for secure digitized medicine”. This is the title of a very interesting and important article in the Journal of Personalised Medine (JPM) as of May 28, 2019. Blockchain as an emerging technology (particularly around the hype …
The phenotype broker: Blockchain and patient phenotype Read more »
May 06, 2019 – Dancing, integrally related to music, likely has its origins close to the birth of Homo sapiens. Some researchers for a long time have hypothesized that there are differences in aptitude, propensity, and need for dancing that …
Creative dancing and the genetic predisposition of it Read more »
Sacco K, Grech G EPMA J 2015;6(1):15 PMID: 26203310 Abstract Breast cancer is a heterogeneous disease that necessitates proper patient classification to direct surgery, pharmacotherapy, and radiotherapy. Despite patients within the same subgroup receiving similar pharmacotherapy, substantial variation in clinical …
Actionable pharmacogenetic markers for prediction and prognosis in breast cancer Read more »
![The Apomediary [Patient Expert] and Personalized Medicine: A Commentary](https://thasso.com/wp-content/uploads/2014/06/Apomediary-II.png)
June 22, 2014 – The individuum (i.e., patient) is the phenotype expert on her/his individualized form of proper disease she/he is suffering from. It is not her/his treating physician, it is not a regulatory person concerned with the safety and …
The Apomediary [Patient Expert] and Personalized Medicine: A Commentary Read more »