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Drugs & Blogs

News & Showcases

Here, you find a seletion of the newest informations on drugs, adverse drug reactions (ADRs), personalized drug safety, genetic predispositions for drug-induced diseases, market withdrawals, etc. Please visit our blogs in English (Theragenomics Blog) or in German (Theragenomik Blog).

Theragenomics Blog
Theragenomik Blog

Drugs Withdrawn from the Market

Short list of drugs and nutriceuticals withdrawn from the market in recent years because of severe adverse drug reactions, that typically occurred in small (sub)groups of patients only. Withdrawals have been worldwide or restricted to selected markets only, which is not further specified here. Note that some of these drugs have been reintroduced in some markets with restrictions. The list is not continued beyond the year 2001.

Active Ingredient

Drug Name

Reason

When

Remarks

Efalizumab

Raptiva

Cases of PML

Apr - 2009

Ribonamant

Acomplia

Suicidality

Feb - 2009

Never Approved in US

Aprotinin

Trasolyl

Increased Mortality

Nov - 2007

Lumiracoxib

Prexige

Liver Toxicity

Sep - 2007

Tegaresod

Zelmac

Cardiovascular Dis.

Mar - 2007

Ximelgatrane

Exanta

Liver Toxicity

Feb - 2007

Valdecoxib

Bextra

Cardiovascular Dis.

Apr - 2005

Natalizumab

Tysabri

Cases of PML

Feb - 2005

Reintroduced w. Restrictions

Rofecoxib

Vioxx

Cardiovascular Dis.

Sep- 2004

Nefazodone

Serzone

Liver Toxicity

Jun - 2004

Ephedra

Hemorrhagic Stroke

Apr - 2004

Kava-Kava

Liver Toxicity

Jan - 2003

Cerivastatin

Baycol

Rhabdomyolysis

Aug - 2001

Links

A selection of links to sites with useful information on all aspects of (personalized) drug safety and genetic backgrounds thereof provided for by a variety of stakeholders.

Swissmedic

EMEA

Drug Injury Network

Documed

MHRA UK

Lawyers Online

BfArM Germany

eMC UK

Wikipedia Portal Medicine

FDA Home

Health Canada

EPA

FDA Patient Safety News

TGA Australia

ECHA European Chemical Agency

FDA MedWatch Safety Alerts

Medsafe New Zealand

OECD Chemical Safety

FDA Genomic Biomarkes

World Health Organization

ATSDR Toxic Chemicals & Disease

Drugs@FDA

Uppsala Monitoring Center

IUCLID5

DailyMed

WorstPills

SNPedia

CYP450 Alleles Nomenclature

CYP450 Drug Interactions

eMedicine

PharmGKB

KEGG

OMIM